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Acute Exacerbation of COPD

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16 Sep 2019

moderate- or high-intensity statin therapy may not reduce exacerbations in adults with COPD (Cochrane Database Syst Rev 2019 Jul 31;7:CD011959)

3 Sep 2019

fluticasone furoate/vilanterol may decrease moderate-to-severe exacerbations compared to umeclidinium/vilanterol in patients with blood eosinophil count ≥ 310 cells per mcL and in former smokers (Lancet Respir Med 2019 Jul 4 early online)

3 Sep 2019

magnitude of reduction in moderate-to-severe exacerbations with fluticasone furoate/umeclidinium/vilanterol compared to umeclidinium/vilanterol may be greater in patients with blood eosinophil count ≥ 310 cells per mcL and in former smokers (Lancet Respir Med 2019 Jul 4 early online)

3 Sep 2019

insufficient evidence to evaluate efficacy and safety of head-to-head comparisons of prophylactic antibiotics in patients with COPD (Cochrane Database Syst Rev 2019 May 24)

3 Sep 2019

insufficient evidence to evaluate efficacy and safety of head-to-head comparisons of prophylactic antibiotics in patients with COPD (Cochrane Database Syst Rev 2019 May 24)

3 Sep 2019

targeted lung denervation may reduce COPD exacerbations needing hospitalization in patients with symptomatic moderate-to-severe COPD (Am J Respir Crit Care Med 2019 Aug 12 early online)

3 Sep 2019

targeted lung denervation may reduce COPD exacerbations needing hospitalization in patients with symptomatic moderate-to-severe COPD (Am J Respir Crit Care Med 2019 Aug 12 early online)

29 Aug 2019

oral mucolytics may reduce exacerbations, hospitalization, and days of disability in adults with chronic bronchitis or COPD (Cochrane Database Syst Rev 2019 May)

29 Aug 2019

oral mucolytics may reduce exacerbations, hospitalization, and days of disability in adults with chronic bronchitis or COPD (Cochrane Database Syst Rev 2019 May)

17 Jul 2019

addition of C-reactive protein (CRP) testing to usual care to guide prescription of antibiotics reduces antibiotic use without impairing health status in patients with acute exacerbation of COPD (N Engl J Med 2019 Jul 11)

17 Jul 2019

addition of C-reactive protein (CRP) testing to usual care to guide prescription of antibiotics reduces antibiotic use without impairing health status in patients with acute exacerbation of COPD (N Engl J Med 2019 Jul 11)

4 Jun 2019

benralizumab as adjunct to inhaled therapy does not reduce COPD exacerbations in patients with moderate to very severe COPD and elevated baseline eosinophil counts (N Engl J Med 2019 May 20 early online)

4 Jun 2019

benralizumab as adjunct to inhaled therapy does not reduce COPD exacerbations in patients with moderate to very severe COPD and elevated baseline eosinophil counts (N Engl J Med 2019 May 20 early online)

4 Jun 2019

low-dose azithromycin for 3 months might reduce treatment failure in adults hospitalized for acute exacerbation of COPD (Am J Respir Crit Care Med 2019 May 3 early online)

4 Jun 2019

low-dose azithromycin for 3 months might reduce treatment failure in adults hospitalized for acute exacerbation of COPD (Am J Respir Crit Care Med 2019 May 3 early online)

4 Jun 2019

prophylactic oral antibiotics may decrease exacerbations in adults with moderate or severe COPD without bronchiectasis (Cochrane Database Syst Rev 2018 Oct 30)

4 Jun 2019

prophylactic oral antibiotics may decrease exacerbations in adults with moderate or severe COPD without bronchiectasis (Cochrane Database Syst Rev 2018 Oct 30)

20 Mar 2019

Global Initiative for Chronic Obstructive Lung Disease (GOLD) global strategy on diagnosis, management, and prevention of COPD (GOLD 2019)

20 Mar 2019

Global Initiative for Chronic Obstructive Lung Disease (GOLD) global strategy on diagnosis, management, and prevention of COPD (GOLD 2019)

5 Mar 2019

daily aspirin use associated with reduced risk of moderate exacerbations and improved dyspnea in adults with COPD (Chest 2018 Dec 26 early online)

5 Mar 2019

daily aspirin use associated with reduced risk of moderate exacerbations and improved dyspnea in adults with COPD (Chest 2018 Dec 26 early online)

3 Dec 2018

hospital-initiated program combining transitional care and long-term self-management support for adults hospitalized due to COPD may reduce subsequent COPD-related hospitalization and emergency department (ED) visits (JAMA 2018 Nov 12 early online)

3 Dec 2018

hospital-initiated program combining transitional care and long-term self-management support for adults hospitalized due to COPD may reduce subsequent COPD-related hospitalization and emergency department (ED) visits (JAMA 2018 Nov 12 early online)

28 Nov 2018

triple therapy of LAMA plus ICS plus LABA may reduce risk of moderate-to-severe exacerbations in patients with advanced COPD (BMJ 2018 Nov 6)

28 Nov 2018

triple therapy of LAMA plus ICS plus LABA may reduce risk of moderate-to-severe exacerbations in patients with advanced COPD (BMJ 2018 Nov 6)

28 Oct 2018

low-dose theophylline as adjunct to inhaled corticosteroids may not reduce frequency of COPD exacerbations in 1 year (JAMA 2018 Oct 16)

22 Jun 2018

beta blockers use does not appear to change improvements compared to no beta blockers at baseline in patients with moderate to very severe COPD receiving long-acting bronchodilator treatment (Chest 2018 Jun)

22 Jun 2018

beta blockers use does not appear to change improvements compared to no beta blockers at baseline in patients with moderate to very severe COPD receiving long-acting bronchodilator treatment (Chest 2018 Jun)

22 Jun 2018

beta blockers use does not appear to change improvements compared to no beta blockers at baseline in patients with moderate to very severe COPD receiving long-acting bronchodilator treatment (Chest 2018 Jun)

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