Subscribe for unlimited access to DynaMed content, CME/CE & MOC credit, and email alerts on content you follow.

Already subscribed? Sign in now

Learn more about CME

Guidance for Antibiotic Use in the Inpatient Setting


You must be a subscriber to see the full topic content.

  • Related Summaries

  • Overview

  • Background

  • KeyboardArrowRight

    Antibiotic Prescribing in the Inpatient Setting

    • Rates of antibiotic use in the inpatient setting

    • KeyboardArrowRight

      Inappropriate antibiotic use in the inpatient setting

      • Definitions of appropriateness

      • Rates of inappropriate antibiotic use

  • KeyboardArrowRight

    Adverse Events with Inpatient Antibiotic Use

    • Rates of antibiotic-associated adverse events

    • Clostridium difficile

    • Development of antibiotic resistance

    • KeyboardArrowRight

      Notable antibiotic-associated adverse events

      • Quinolones

      • Aminoglycosides

      • Vancomycin

      • Linezolid

      • Daptomycin

      • Cotrimoxazole (trimethoprim-sulfamethoxazole [TMP-SMX])

      • Metronidazole

      • Clindamycin

      • Macrolides

      • Tetracyclines

      • Beta-lactam antibiotics

  • KeyboardArrowRight

    Inpatient Antimicrobial Stewardship Programs

    • General antibiotic stewardship considerations

    • Institutional antibiograms and resistance data reporting

    • Preauthorization and prospective audit and feedback strategies

    • Rational pharmacokinetic and pharmacodynamic antibiotic dose adjustment

    • Renal dosing

  • KeyboardArrowRight

    Antibiotic Recommendations for Specific Conditions

    • KeyboardArrowRight

      Critical care and septic patients

      • General considerations for antibiotic use in critical care

      • Sepsis and septic shock

    • Central line-associated infections

    • KeyboardArrowRight


      • Community-acquired pneumonia requiring admission

      • Hospital-acquired pneumonia

      • Ventilator-acquired pneumonia

    • Febrile neutropenia

    • Complicated urinary tract infections (UTI)

    • Osteomyelitis

    • KeyboardArrowRight

      Skin and soft tissue infections

      • Necrotizing fasciitis

      • Cellulitis

    • Bacterial meningitis

    • KeyboardArrowRight

      Gastrointestinal infections

      • Clostridium difficile infection

      • Acute pancreatitis

      • Diverticulitis

    • Complicated intra-abdominal infections

    • KeyboardArrowRight

      Surgical site infections

      • Prophylaxis of surgical site infections

      • Treatment of surgical site infections

  • KeyboardArrowRight

    Guidelines and Resources

    • KeyboardArrowRight


      • International guidelines

      • United States guidelines

    • Review articles

  • KeyboardArrowRight

    Quality Improvement

    • Choosing Wisely

    • Choosing Wisely Australia

  • Patient Information

  • KeyboardArrowRight


    • General references used

    • Recommendation grading systems used

    • DynaMed Editorial Process

    • Special acknowledgements

    • How to cite

Topic Editor
Gail Scully MD, MPH

Assistant Professor of Medicine, Department of Medicine, and Medical Director, Antimicrobial Stewardship, UMASS Memorial Medical Center; Massachusetts, United States; Hospital Epidemiologist, Fairlawn Rehabilitation Hospital; Massachusetts, United States

Conflicts of Interest

Dr. Scully declares no relevant financial conflicts of interest.

Deputy Editor
Vito Iacoviello MD, FIDSA

Deputy Editor of Infectious Diseases, Immunology and Rheumatology, Dynamed; Massachusetts, United States; Assistant Professor of Medicine, Harvard Medical School; Massachusetts, United States; Chief of the Division of Infectious Diseases, Mount Auburn Hospital; Massachusetts, United States

Conflicts of Interest

Dr. Iacoviello declares no relevant financial conflicts of interest.