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Drug Interactions

Use the search fields to look up two or more drugs for potential interactions.

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Severity Index

DEFINITIONS
DOCUMENTATION
  • CONTRAINDICATED

    The drugs are contraindicated for concurrent use.

  • MAJOR

    The interaction may be life-threatening and/or require medical intervention to minimize or prevent serious adverse effects.

  • MODERATE

    The interaction may result in exacerbation of the patient’s condition and/or require an alteration in therapy.

  • MINOR

    The interaction would have limited clinical effects. Manifestiations may include an increase in the frequency or severity of the side effects but generally would not require a Major alteration in therapy.

  • UNKNOWN