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Long-acting Beta-2 Agonists for Asthma in Adults and Adolescents

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  • Related Summaries

  • Overview

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    Recommendations

    • Global Initiative for Asthma (GINA) guidelines

    • British Thoracic Society/Scottish Intercollegiate Guideline Network (BTS/SIGN) guidelines

  • LABAs and Dosing Regimens

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    Efficacy

    • Monotherapy

    • Combination with inhaled steroids as initial therapy

    • Add-on therapy for inadequately controlled asthma

    • Step down therapy

    • Management of acute exacerbations

    • Effect of beta 2-adrenergic receptor (ADRB2) polymorphisms

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    Comparative Efficacy

    • Multiple comparisons (mixed treatment comparisons)

    • Long-acting beta-2 agonists (LABAs) vs. short-acting beta-2 agonists (SABAs)

    • Long-acting beta-2 agonists (LABAs) vs. increasing inhaled corticosteroid dose

    • LABAs vs. leukotriene antagonists

    • LABAs vs. theophylline

    • Salmeterol/fluticasone vs. formoterol/budesonide

    • Formoterol/budesonide vs. other treatments

    • Combination inhaler vs. separate inhalers

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    Risk for Serious Adverse Events

    • Overview of serious adverse effects

    • FDA Warning

    • Drug Class Reviews

    • Salmeterol-Specific Risk Data

    • Formoterol-specific risk data

    • Comparative Risk Data (Salmeterol vs. Formoterol)

    • Other adverse effects

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    Guidelines and Resources

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      Guidelines

      • International guidelines

      • United Kingdom guidelines

      • Australian and New Zealand guidelines

      • Central and South American guidelines

    • Review articles

  • Patient Information

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    ICD Codes

    • ICD-9 codes

    • ICD-10 codes

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    References

    • General references used

    • Recommendation grading systems used

    • DynaMed Editorial Process

    • Special acknowledgements

    • How to cite

Deputy Editor
Terence K. Trow MD, FACP, FCCP
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Affiliations

Deputy Editor of Pulmonary, Critical Care, and Sleep Medicine; Connecticut, United States; Ex-Director of the Yale Pulmonary Vascular Disease Program, Associate Clinical Professor of Medicine, Yale University School of Medicine; Connecticut, United States

Conflicts of Interest

Dr. Trow declares no relevant financial conflicts of interest.

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