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Staphylococcus aureus

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    Pathogen

    • Classification

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      Virulence factors

      • Cytolysins

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        Superantigens

        • Toxic shock syndrome toxin 1 (TSST-1)

        • Staphylococcal enterotoxins

      • Exfoliatins

      • Other virulence factors

    • Biofilm formation

    • Habitat

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    Epidemiology

    • Geographic distribution

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      Incidence and prevalence

      • United States

    • Risk factors

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    Host-Pathogen Interaction

    • Transmission

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      Pathogenesis

      • Mechanisms of resistance

    • Immune response

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    Clinical Features

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      Toxin-mediated diseases

      • Staphylococcal toxic shock syndrome (STSS)

      • Staphylococcal food poisoning

      • Scalded skin syndrome (Ritter disease)

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      Infection-mediated diseases

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        Skin and soft tissue infections

        • Impetigo

        • Folliculitis

        • Skin abscess

        • Furuncles and carbuncles

        • Erysipelas

        • Cellulitis

        • Mastitis

        • Necrotizing fasciitis

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        Systemic infections

        • Bacteremia

        • Infective Endocarditis (IE)

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        Pulmonary Infections

        • Pneumonia

        • Necrotizing pneumonia

        • Parapneumonic effusion and empyema

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        Bone, joint, and muscle infections

        • Osteomyelitis

        • Septic arthritis

        • Prosthetic joint infection (PJI)

        • Pyomyositis

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    Diagnosis

    • Principles of diagnosis

    • Culture-based identification

    • Antibiotic resistance testing

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    Treatment

    • Principles of treatment

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      Medications

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        Antistaphylococcal penicillins

        • Nafcillin and Oxacillin

        • Dicloxacillin

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        Cephalosporins

        • Cefazolin

        • Ceftriaxone

        • Cephalexin

      • Adjunctive rifampin

      • Comparative efficacy of empiric vancomycin and beta-lactam antibiotics

      • Comparative efficacy of beta-lactam antibiotics

  • Prognosis

  • Prevention and Infection Control

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    Guidelines and Resources

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      Guidelines

      • International guidelines

      • United States guidelines

      • United Kingdom guidelines

      • Canadian guidelines

      • European guidelines

      • Central and South American guidelines

    • Review articles

    • MEDLINE search

  • Patient Information

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    ICD Codes

    • ICD-10 codes

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    References

    • General references used

    • Synthesized Recommendation Grading System for DynaMed

    • DynaMed Editorial Process

    • Special acknowledgements

    • How to cite

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