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Statins

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  • Related Summaries

  • Overview

  • Mechanism of Action

  • Efficacy for Cardiovascular Disease Prevention

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    Efficacy for Other Outcomes

    • Statins in heart failure

    • Statins for blood pressure reduction

    • Statins for lipid lowering

    • Statins and venous thromboembolism

    • Statins and aortic stenosis

    • Statins and chronic kidney disease

    • Statins and infections

    • Statins and dementia

    • Statins and osteoporosis

    • Statins and ocular disease

    • Statins and pancreatitis

    • Statins and multiple sclerosis

    • Statins and erectile dysfunction

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    Comparative Efficacy

    • Comparative efficacy for clinical outcomes

    • Comparative efficacy for lipid levels

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    Contraindications, Precautions and Adverse Effects

    • Contraindications

    • Statins and cancer risk

    • Statins and myopathy

    • Statins and hepatotoxicity

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      Adverse effects

      • Diabetes mellitus

      • Other adverse effects

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    Interactions

    • Drug-drug interactions

    • Drug-food interactions

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    Patient Monitoring

    • Recommended laboratory monitoring

    • Usefulness of routine monitoring

    • C-reactive protein

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    Dosing

    • Dose intensity

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      Alternative Dosing

      • Alternate-day dosing

      • Nightly dosing

      • Increased dosing

      • Drug holiday

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    Prescribing Information

    • See related topics for details

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      Drug brands

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        Atorvastatin brands

        • United States brands

        • Canadian brands

        • United Kingdom brands

        • Australian brands

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        Fluvastatin brands

        • United States brands

        • Canadian brands

        • United Kingdom brands

        • Australian brands

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        Lovastatin brands

        • United States brands

        • Canadian brands

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        Pitavastatin brands

        • United States brands

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        Pravastatin brands

        • United States brands

        • Canadian brands

        • United Kingdom brands

        • Australian brands

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        Rosuvastatin brands

        • United States brands

        • Canadian brands

        • United Kingdom brands

        • Australian brands

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        Simvastatin brands

        • United States brands

        • Canadian brands

        • United Kingdom brands

        • Australian brands

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    Adherence

    • Nonadherence common

    • Adherence associated with reduced mortality

    • Interventions to improve adherence

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    Quality Improvement

    • Physician Quality Reporting System Quality Measures

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    Guidelines and Resources

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      Guidelines

      • International guidelines

      • United States guidelines

      • United Kingdom guidelines

      • Canadian guidelines

      • European guidelines

    • Review articles

    • MEDLINE search

  • Patient Information

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    References

    • Recommendation grading systems used

    • DynaMed Editorial Process

    • Special acknowledgements

    • How to cite

Topic Editor
Vijay Nambi MD, PhD
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Affiliations

Associate Professor, Section of Cardiovascular Research, Division of Atherosclerosis and Vascular Medicine, Department of Internal Medicine, Baylor College of Medicine; Texas, United States

Conflicts of Interest

Dr. Nambi declares no relevant financial conflicts of interest.

Deputy Editor
Peter Oettgen MD
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Affiliations

Editor in Chief, DynaMed; Cardiologist, Beth Israel Deaconess Medical Center; Massachusetts, United States; Associate Professor of Medicine, Harvard Medical School; Massachusetts, United States

Conflicts of Interest

Dr. Oettgen declares no relevant financial conflicts of interest.

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