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Secondary Prevention of Coronary Artery Disease


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    Overview and Recommendations

    • Background

    • Evaluation

    • Management

  • Related Summaries

  • Description

  • Overview

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    Cardiac Rehabilitation

    • Recommendations (cardiac rehabilitation)

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      Efficacy (cardiac rehabilitation)

    • Disease management and secondary prevention programs

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    • Recommendations for secondary prevention

    • Evidence (diet)

    • Omega-3 fatty acids

    • Moderate alcohol consumption

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    Physical Activity

    • Recommendations for secondary prevention

    • Evidence (physical activity)

    • Sexual activity

  • Weight

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    Smoking Cessation

    • Related summaries for smoking cessation

    • Recommendations for smoking cessation

    • Evidence for smoking cessation

  • Medication Adherence

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    Antihypertensive Therapies

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      Blood pressure

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        Target blood pressure (evidence)

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      Renin-angiotensin-aldosterone system inhibitors

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        Angiotensin converting enzyme (ACE) inhibitors

        • Recommendations (ACE inhibitors)

        • Efficacy (ACE inhibitors)

        • Individual ACE inhibitor trials

        • Adverse effects and precautions (ACE inhibitors)

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        Angiotensin receptor blockers (ARBs)

        • Recommendations (ARBs)

        • Comparative efficacy

        • Combination ACE inhibitors plus ARBs

      • Aldosterone blockade

      • Renin inhibitor

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      Beta blockers

      • Recommendations (beta blockers)

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        Efficacy (beta blockers)

      • Adverse effects and precautions (beta blockers)

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      Calcium channel blockers

      • Recommendations (calcium channel blockers)

      • Efficacy (calcium channel blockers)

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    • Recommendations for statins for secondary prevention from professional organizations

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      • Efficacy (statins for secondary prevention)

      • Comparative efficacy of statins

    • PCSK9 inhibitors

    • Fibrates

    • Other medications

  • Antiplatelets and Anticoagulants

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    Diabetes Management

    • Recommendations

    • Glucose-lowering medications

  • Influenza Vaccination

  • Monoclonal antibodies

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    Interventions that are Ineffective or Not Well Studied

    • Omega-3 fatty acids

    • Niacin

    • Vitamins

    • Hormone replacement therapy

    • Colchicine

    • Methotrexate

    • Other cardiovascular medications

    • Periodontal therapy

    • Chelation therapy

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      Other alternative treatments

      • L-arginine

      • Creatine supplementation

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    Quality Improvement

    • Physician Quality Reporting System Quality Measures

    • Quality and Outcomes Framework Indicators

    • Quality improvement evidence

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    Guidelines and Resources

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      • United States guidelines

      • United Kingdom guidelines

      • Canadian guidelines

      • European guidelines

      • Australian and New Zealand guidelines

  • Patient Information

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    • General references used

    • Recommendation grading systems used

    • Synthesized Recommendation Grading System for DynaMed

    • DynaMed Editorial Process

    • Special acknowledgements

    • How to cite

Topic Editor
Maria Sciammarella MD

Associate Clinical Professor, University of California, San Francisco; California, United States

Conflicts of Interest

Dr. Sciammarella declares no relevant financial conflicts of interest.

Recommendations Editor
Esther Jolanda van Zuuren MD

Head of Allergy, Dermatology, and Venereology, Leiden University Medical Centre; Netherlands

Conflicts of Interest

Dr. van Zuuren declares no relevant financial conflicts of interest.

Deputy Editor
Peter Oettgen MD

Editor in Chief, DynaMed; Cardiologist, Beth Israel Deaconess Medical Center; Massachusetts, United States; Associate Professor of Medicine, Harvard Medical School; Massachusetts, United States

Conflicts of Interest

Dr. Oettgen declares no relevant financial conflicts of interest.